HPLC of a 2-amino-2-oxazoline: application to pharmacokinetic studies in dogs
Summary
Type: HPLC Application #: 103960
Detection: UV, 235nm Conditions: eluent: methanol - 0.1M ammonium acetate (5:95, v/v) containing 2mM Na heptanesulphonate, 1% tetrahydrofuran and 0.2% triethylamine, pH adjusted to 4.5 with H3PO4 flow rate 1ml/min Authors: Damaj MI Source: J Pharm Sci 79 (1990) 516 - 518
Details
Legend: Fig. 1. Chromatograms of A) blank plasma, B) plasma spiked with 125µg/l
COR3224, C) plasma spiked with 1000µg/l COR3224, 1. COR3224, 2. ortho-O-methyl
derivative of 1. (int. std.).